By Hubert Dwight
Saxenda, a prescription medication, has gained attention for its role in helping individuals achieve their weight loss goals.
But is Saxenda the right choice for you? This detailed review aims to provide comprehensive insights into how Saxenda works, its benefits, potential side effects, and who might be the ideal candidate for this treatment.
In this review, we will explore the mechanism of action of Saxenda, how it differs from other weight loss medications, and the clinical evidence supporting its use.
We will also discuss the practical aspects of using Saxenda, such as the administration process, cost considerations, and insurance coverage.
For those specifically looking into the Saxenda Canada cost, understanding the financial aspect and whether it's covered by your insurance is crucial.
By the end of this review, you will have a clearer understanding of whether Saxenda aligns with your weight management needs and if it could be a viable part of your health journey.
What is Saxenda?
Saxenda (liraglutide) is a prescription medication approved by the FDA for chronic weight management.
It belongs to a class of drugs called GLP-1 receptor agonists. Originally developed for treating type 2 diabetes under the name Victoza, Saxenda is specifically formulated for helping individuals achieve and maintain weight loss.
Saxenda works by mimicking a hormone called glucagon-like peptide-1 (GLP-1) that targets areas of the brain regulating appetite and food intake.
Saxenda uses and indications
Saxenda is prescribed for:
- Adults with a BMI of 30 or higher (obesity): These individuals do not need to have other weight-related conditions to be eligible for Saxenda.
- Adults with a BMI of 27 or higher (overweight) with at least one weight-related condition: These conditions include type 2 diabetes, hypertension, or dyslipidemia.
- Adolescents aged 12-17 with a body weight above 60 kg and obesity: Saxenda can also be used for younger individuals who meet specific weight criteria and are experiencing obesity.
How is Saxenda administered?
Saxenda is administered via a subcutaneous injection, meaning it is injected under the skin. It comes in a prefilled pen, which makes it easy to use. Here’s how it is typically administered:
- Injection sites: The abdomen, thigh, or upper arm.
- Dosing schedule: The dose gradually increases over several weeks to minimize gastrointestinal side effects. Starting with a lower dose and gradually increasing it helps the body adjust to the medication.
- Frequency: It is taken once daily, at any time, with or without food.
Benefits of Saxenda
Saxenda offers several benefits for weight management:
- Effective weight loss: Clinical studies have shown that individuals using Saxenda, in combination with a reduced-calorie diet and increased physical activity, achieve significant weight loss compared to those using a placebo.
- Improved cardiovascular health: Weight loss can lead to reductions in blood pressure, improved cholesterol levels, and better blood sugar control, all contributing to overall cardiovascular health.
- Reduced risk of weight-related conditions: Losing weight with Saxenda can help lower the risk of developing or worsening conditions like type 2 diabetes, hypertension, and sleep apnea.
Potential side effects and risks
Like all medications, Saxenda has potential side effects and risks. Common side effects include:
- Gastrointestinal issues: Nausea, diarrhea, constipation, and vomiting are common, especially when starting the medication or increasing the dose.
- Low blood sugar (hypoglycemia): This is more common in people with type 2 diabetes who are also taking other glucose-lowering medications.
- Decreased appetite: While this is often a desired effect, it can sometimes lead to insufficient calorie intake.
Serious but rare side effects include:
- Pancreatitis: Inflammation of the pancreas.
- Gallbladder problems: Including gallstones.
- Kidney problems: Worsening of kidney function.
- Suicidal thoughts or behaviors: Patients should be monitored for changes in mood or behavior.
- Increased heart rate: Regular monitoring of heart rate is recommended.
Who should consider Saxenda?
Saxenda may be suitable for individuals who:
- Adults with a BMI of 30 or higher.
- Have a BMI of 27 or higher and suffer from at least one weight-related condition such as type 2 diabetes, hypertension, or dyslipidemia.
- Are adolescents (12-17 years) with obesity and a body weight above 60 kg.
- Have not achieved significant weight loss through diet and exercise alone.
- Are willing to commit to lifestyle changes in conjunction with the medication.
Who should not use Saxenda?
Saxenda is not recommended for individuals who:
- Have a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- Are allergic to liraglutide or any other ingredients in Saxenda.
- Are pregnant or planning to become pregnant, as it may harm the fetus.
- Have a history of severe hypersensitivity reactions to GLP-1 receptor agonists.
- Have severe gastrointestinal disease, such as gastroparesis.
Using Saxenda safely and effectively
To ensure safe and effective use of Saxenda:
- Follow dosing instructions: Adhere to the prescribed dosing schedule, and do not skip doses.
- Monitor side effects: Report any serious or persistent side effects to your healthcare provider.
- Check blood sugar levels: If you have diabetes, monitor your blood sugar levels regularly.
- Combine with lifestyle changes: Use Saxenda in conjunction with a reduced-calorie diet and increased physical activity for the best results.
- Regular check-ups: Schedule regular appointments with your healthcare provider to monitor progress and make any necessary adjustments to your treatment plan.
Cost of Saxenda and insurance coverage
The cost of Saxenda, a weight loss medication, varies widely and is influenced by several factors, including insurance coverage.
Saxenda is a GLP-1 receptor agonist administered via daily injection, and its price can be substantial without insurance.
The extent of insurance coverage for Saxenda depends on your specific health insurance plan and individual health needs.
Some insurance plans may cover part or all of the cost if Saxenda is prescribed for weight management in individuals with a BMI of 27 or higher, particularly if there are other weight-related health conditions present​​.
It's advisable to discuss with your healthcare provider and insurance company to understand your coverage and potential costs
Lifestyle changes when using Saxenda
For the best results, it’s important to incorporate lifestyle changes while using Saxenda:
- Diet: Adopt a balanced, reduced-calorie diet rich in fruits, vegetables, lean proteins, and whole grains.
- Exercise: Engage in regular physical activity, aiming for at least 150 minutes of moderate-intensity exercise per week.
- Behavioral changes: Practice mindful eating, manage stress, and seek support from weight loss programs or counseling if needed.
How long does it take to see results with Saxenda?
Weight loss with Saxenda typically begins within the first few weeks of treatment. Most individuals experience the most significant weight loss in the first three to six months.
Continued, gradual weight loss is often observed throughout treatment, especially when combined with lifestyle changes.
Final thoughts
Saxenda can be an effective tool for weight loss and weight management in individuals struggling with obesity or overweight conditions.
It should be used as part of a comprehensive treatment plan that includes dietary changes, physical activity, and behavioral modifications.
Always consult with a healthcare provider to determine if Saxenda is the right option for you.
